In part 1 I covered issues related to the effect of TRT (Testosterone Replacement Therapy) on male fertility. Here I will outline options for men to increase endogenous testosterone production by non-TRT means, and ways to speed up spermatogenesis for those who chose to go the TRT route…
The prevalence of testosterone deficiency (aka hypogonadism or Late Onset Hypogonadism), defined as total testosterone (TT) at or below 300 ng/dl is close to 40% in men aged 45 years and older presenting to primary care offices in the US.1 Year 2006 is was estimated that more than 13.8 million men over 45 years of age visiting a primary care doctor in the United States have symptomatic androgen deficiency.1
A large international web survey using the Aging Males’ Symptoms (AMS) questionnaire showed the prevalence of symptomatic testosterone deficiency to be 80% in men aged 16–89 (mean 52 years).2 It is notable that in the survey 40% of respondent were at younger ages when ‘Late Onset Hypogonadism’ is generally not believed to be occurring.2 The surprisingly high prevalence of raised scores indicative of testosterone deficiency in the younger age groups may be due to the increasing prevalence of conditions in these age groups known to reduce testosterone levels, such as obesity 3-7 and chronic work stress. 8-10 Stress-induced cortisol elevation, by increasing SHBG, lowers the free active fraction of testosterone and thereby reduces its action.11
This large and rising prevalence of testosterone deficiency is gaining recognition among doctors and patients alike. However, while testosterone replacement therapy (TRT) confers great benefits to men with sup-optimal testosterone levels, it also comes with some side-effects which are especially relevant for men who wish to have a family…Many testosterone users and even clinicians 12 are unaware that testosterone supplementation suppresses the hypothalamic-pituitary-gonadal (HPG) axis and may result in infertility…
Whey protein has become a staple nutritional supplement with both athletic populations requiring the highest possible quality protein to help recuperate from exercise, and those interested in the various health and disease fighting benefits of whey.
However, whey is a complex protein which leads to various questions regarding this biologically active protein. Some of this confusion has stemmed from the marketing efforts of various companies competing for sales in a very competitive market. Some of the confusion stems from a simple misunderstanding of the science of whey.
This Q&A will attempt to address some of the most common questions regarding whey as it applies to some of the major differences between types of whey, such as whey concentrates and whey isolates and other common sources of confusion. For in-depth information on whey and its many potential health benefits, read the “50 Shades Of Whey”
Q1:“What are the essential differences and advantages/disadvantages of each type of whey protein? Isolate, concentrates?”
DHEA (dehydroepiandrosterone) is most known for being a pro-hormone which in the body gets converted to testosterone and estrogen. It is a long held view that DHEA exerts all its effects via conversion to testosterone and estrogen. However, recent studies show that DHEA also has several interesting non-hormonal actions…
When you do a typical bench press rep, it’s a little known fact that a good percentage of the last part of the movement (as you come to lockout) is used by the body to decelerate the bar. The lighter the weight you use, the greater this percentage is. The heavier you go, the lower this percentage is.
This is a safety mechanism used by the body to prevent joint injury. It senses the load on the muscles and joints and will actively work against the movement in order to slow down the resistance and protect the joints.
A few days ago, Jan 29th 2014, a controversial study was published showing that men aged 65 years and older, had a two-fold increase in the risk of heart attack in the 90 days after filling an initial testosterone therapy (TT) prescription, regardless of cardiovascular disease history. Among younger men below 65 years of age with a history of heart disease, the study reported two to three-fold increased risk of MI in the 90 days following an initial TT prescription (and no excess risk was found in younger men without such a history).
This study has stirred up heated discussions and media headlines. Let’s dissect it and look under the hood…
Is good form during weight lifting essential to gaining muscle mass? Many think good form is an essential factor, but is it? The answer may surprise you!
This is a very simple and very effective version of the plank. It’s done using one of your arms set directly out to the side like the outrigger on a canoe. This allows you to target the deep muscles of the core that are responsible for rotational stabilization (the obliques and transversus).
Many studies have highlighted the importance of investigating all major hormones, and correcting deficiencies and imbalances if present.[1-8] Given the known mechanisms of testosterone and GH/IGF-1 in building muscle (and possibly also DHEA in elderly) it is reasonable that age-related low levels of anabolic hormones contribute over time to sarcopenia and frailty.[1, 2, 4, 7, 9, 10]
Thus, multiple small effects in aggregate can lead to adverse loss of muscle and disability. In this scenario, if replacement was to occur, it would require lower doses of multiple anabolic hormones. An added benefit to this approach would be fewer side effects from the use of lower hormone doses . In addition, multiple anabolic hormone replacement might also have beneficial additive and/or synergistic effects.[11-13]
A notable study investigated whether supplementation with testosterone and GH together, in physiological doses, results in greater improvements in body composition and muscle performance in older men, compared to testosterone supplementation alone…
The consequences of low testosterone levels have been primarily investigated in middle-age and older men. However, low-T in young men aged 20-39 years can confer health risks as well…